The Smithsonian Science Education Center uses inquiry science to change how classrooms look, feel, and work, and helps the nation's teachers rekindle their yearning to discover and learn. Deep relationships with teachers, educational leaders, and community partners through the Leadership and Assistance for Science Education Reform (LASER) model are changing the forecast for science education in our country and across the world. The LASER model describes the infrastructure necessary to create systemic, sustainable science education reform. When implemented to fidelity, this model helps schools, districts, and states provide opportunities for all students to succeed in their adult lives. Through this model we are preparing a scientifically literate citizenry equipped to take on some of the greatest challenges our society faces.